The Maryville University women's lacrosse team had five selections to the 2025 Intercollegiate Women's Lacrosse Coaches Association All-American Teams. Junior attacker Helen Bae earned first-team All-America honors, grad student midfielder Chloe Elliott, junior defender Haley Ritchie and junior midfielder Marissa Zeno were voted second team, while sophomore attacker Natalie Tomljenovic was a third-team honoree.
 
Bae was the unanimous pick as the Great Lakes Valley Conference Attacker of the Year and had 72 goals and 25 assists for 97 points this season. In addition, she came up with 145 draw controls and ranks 11th in the country at 6.90 per game.
 
Elliott led the team with 76 goals to go along with 17 assists for 92 points on the season. She topped the team with 54 ground balls and added 45 draw controls. Ritchie has been one of the defensive leaders on a team that ranked second in scoring defense nationally. She finished with 23 ground balls, 22 caused turnovers and has been a critical presence on the team's defensive clearing squad.
 
Zeno was a standout on both ends of the field. She finished with 69 goals and led the team with 40 assists for a team-leading 109 points, to rank seventh nationally. Zeno contributed 39 draw controls to go along with 31 ground balls and 21 caused turnovers. Tomljenovic notched 51 goals and was second on the team with 38 assists for 89 total points. She added 26 ground balls and 11 caused turnovers.
 
The Saints finished the season with a school record for wins and were 19-2 on the campaign. Maryville won its first GLVC Tournament title and reached the 2025 NCAA Division II Tournament Quarterfinals.